In an open letter that was published in a major French newspaper, Gerard Depardieu denied the rape and sexual attack claims made against him.
In a statement that was published in Le Figaro, the French actor said, "I have never, ever hurt a woman."
"I have only my word to defend myself in the media court and the lynching that has been planned for me," the 74-year-old said.
In 2021, the character from the movie "Green Card" was accused of rape.
In August 2018, a woman said that the star had raped and beaten her in Paris.
At the time, Depardieu's lawyer told the French news agency AFP that his client "totally denied" the accusation and that the probe should not have been made public.
Earlier this year, 13 more women said that Depardieu had sexually assaulted or harassed them. A French news website, Mediapart, looked into these claims.
The actor's lawyer said that he "officially denies all the charges that could be criminal."
In a long message that was published on the opinion pages of Le Figaro, Depardieu said, "I can't take what I hear and read about myself anymore. I thought I didn't care, but I don't. All of this bothers me. Even worse, it kills me.
"Hurting a woman would be like kicking my own mother in the stomach," he said.
He also said that the woman who said he raped her came to his room "on her own volition."
In an interview with French radio station France Info on Monday morning, the lawyer for his accuser said she was "shocked and scandalized" by the letter. This was carried by the news site Deadline.
"Mr. Depardieu says he's telling the truth, but the courts will definitely not agree with him," she said.
Depardieu wrote in response to the separate claims of sexual assault and harassment, "I've often done things that others wouldn't dare to do: pushed limits, shook certitudes, habits on the set between two takes, between two tensions... to get a laugh.
"Everyone didn't laugh. If, by trying to live in the moment fully, I hurt or shocked someone, it was never my goal to do so. Please forgive me for acting like a child who just wanted to have fun in a museum.
Depardieu has been in more than 170 movies. His big break came with Les Valseuses (Going Places) in 1973.
In 1990, he got the award for best actor at Cannes for his role in Cyrano de Bergerac. He was also nominated for an Oscar for the same role.
Green Card, a comedy made in the same year in English, gave him more attention outside of the French-speaking world.
Off-screen, he's been in the news in the past few years for criticizing French tax rules and moving to Belgium to protest.
In 2013, he became a Russian citizen. President Vladimir Putin signed the document that made him a citizen.
But last year, he spoke out against the war in Ukraine and accused Vladimir Putin of "crazy, unacceptable excesses" in the country.
Depardieu said that the Russian people were not to blame for the actions of their boss.
Dmitry Peskov, who is Mr. Putin's spokesman, said that the actor probably didn't fully understand what was going on in Ukraine and offered to describe it.